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Glyphosate functions as a competitive inhibitor of the shikimate pathway (check Figure 1) in microorganisms, parasites, and plants, thereby hindering the activity of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), which catalyzes the sixth step in the shikimate pathway [18,19]

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Increased oxidative stress in cancer cells upregulates NADPH oxidase, which results in distinct and independent fluxes between the cytosol and mitochondria (Niu et al